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                4月26日 毛佳飞:A Membrane Protein Safari by Sensitivity-Enhanced Solid-State NMR Spectroscopy(化学优秀学者系列学术〖报告)



                Dr. Mao was born in 1983 in Suzhou, China. In 2005 he received his Bachelor degree in Chemistry from Nanjing University after completing his undergraduate study in the Department for Intensive Instruction (DII), one of the few elite undergraduate programs charted by the Ministry of Education. He did his master thesis on light-activatable anticancer drugs under the supervision of Prof. Zijian Guo in the State Key Laboratory of Coordination Chemistry (SKLCC) and obtained the Master Degree in inorganic chemistry in 2008 with a following publication on Chem. Commun.. He then moved to the Centro di Risonanze Magnetiche (CERM) in University of Florence in Italy, a leading center in biological NMR spectroscopy housing one of the EU large scale facilities, and did his training on biological solid-state NMR (SSNMR) under the supervision of Prof. Ivano Bertini. He published four papers on J. Am. Soc. Chem. there and was the main NMR contributor to the first high-resolution structure of amyloid-beta fibrils. Shortly after passing his Ph.D. defense in structural biology with the level of excellence, he joined Prof. Clemens Glaubitz’s SSNMR team in the Biological Magnetic Resonance Center (BMRZ) in Goethe University of Frankfurt am Main in Germany. As a postdoc researcher, he carried out researches on both SSNMR applications on challenging membrane proteins and methodology development featuring the sensitivity enhancement technique dynamic nuclear polarization (DNP). He has published a number of high-impact papers since he joined BMRZ, including four papers on J. Am. Soc. Chem. and Nat. Chem. Biol. His works have been well received by the research communities as shown by his growing list of talks delivered on important conferences including GRC, ISMAR and EUROMAR. His current research interests are mainly on the molecular mechanisms of disease-related membrane proteins, next-generation optogenetic tools and novel easy-to-use NMR techniques for biologists.